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The value of potassium, pH and D-dimer levels in early diagnosis of acute mesenteric ischemia: an experimental study on rats
INTRODUCTION: The aim of this randomized controlled experimental study was to evaluate the efficacy of potassium, pH and D-dimer levels in blood, as well as potassium and pH levels in peritoneal lavage fluid, in the early diagnosis of acute mesenteric ischemia. MATERIAL AND METHODS: This study was c...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Termedia Publishing House
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7811331/ https://www.ncbi.nlm.nih.gov/pubmed/33488876 http://dx.doi.org/10.5114/aoms.2019.84225 |
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author | Hot, Semih Egin, Seracettin Ilhan, Mehmet Bademler, Suleyman Dikker, Okan Aciksari, Kurtulus Kamali, Gulcin Seckin, Ismail Tanriverdi, Gamze Kamali, Sedat Guloglu, Recep |
author_facet | Hot, Semih Egin, Seracettin Ilhan, Mehmet Bademler, Suleyman Dikker, Okan Aciksari, Kurtulus Kamali, Gulcin Seckin, Ismail Tanriverdi, Gamze Kamali, Sedat Guloglu, Recep |
author_sort | Hot, Semih |
collection | PubMed |
description | INTRODUCTION: The aim of this randomized controlled experimental study was to evaluate the efficacy of potassium, pH and D-dimer levels in blood, as well as potassium and pH levels in peritoneal lavage fluid, in the early diagnosis of acute mesenteric ischemia. MATERIAL AND METHODS: This study was conducted at the Istanbul University Center of Experimental Medicine after having received approval from the Istanbul University animal testing ethics committee. Male albino Wistar rats (n = 24; 250 to 350 g) were divided into two control groups and two ischemic groups. Levels of potassium, pH, and D-dimer in blood and levels of potassium and pH in peritoneal lavage fluid were analyzed for 1 h and 2 h after the induced acute mesenteric ischemia procedure. The degree of ischemic injury was determined using the histopathological damage score in tissue samples taken from the terminal ileum. RESULTS: Ischemic groups had statistically significant differences in potassium and pH in blood and peritoneal lavage fluid compared to non-ischemic groups (p < 0.05). There was no significant difference between control and ischemic groups in terms of D-dimer and histologic grading results after 1 h (p = 0.132, p = 0.475 respectively), while there was a significant difference between control and ischemic groups after 2 h (p < 0.05). CONCLUSIONS: The levels of potassium, pH, and D-dimer could be useful in daily practice for the early diagnosis of acute mesenteric ischemia. |
format | Online Article Text |
id | pubmed-7811331 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Termedia Publishing House |
record_format | MEDLINE/PubMed |
spelling | pubmed-78113312021-01-22 The value of potassium, pH and D-dimer levels in early diagnosis of acute mesenteric ischemia: an experimental study on rats Hot, Semih Egin, Seracettin Ilhan, Mehmet Bademler, Suleyman Dikker, Okan Aciksari, Kurtulus Kamali, Gulcin Seckin, Ismail Tanriverdi, Gamze Kamali, Sedat Guloglu, Recep Arch Med Sci Experimental Research INTRODUCTION: The aim of this randomized controlled experimental study was to evaluate the efficacy of potassium, pH and D-dimer levels in blood, as well as potassium and pH levels in peritoneal lavage fluid, in the early diagnosis of acute mesenteric ischemia. MATERIAL AND METHODS: This study was conducted at the Istanbul University Center of Experimental Medicine after having received approval from the Istanbul University animal testing ethics committee. Male albino Wistar rats (n = 24; 250 to 350 g) were divided into two control groups and two ischemic groups. Levels of potassium, pH, and D-dimer in blood and levels of potassium and pH in peritoneal lavage fluid were analyzed for 1 h and 2 h after the induced acute mesenteric ischemia procedure. The degree of ischemic injury was determined using the histopathological damage score in tissue samples taken from the terminal ileum. RESULTS: Ischemic groups had statistically significant differences in potassium and pH in blood and peritoneal lavage fluid compared to non-ischemic groups (p < 0.05). There was no significant difference between control and ischemic groups in terms of D-dimer and histologic grading results after 1 h (p = 0.132, p = 0.475 respectively), while there was a significant difference between control and ischemic groups after 2 h (p < 0.05). CONCLUSIONS: The levels of potassium, pH, and D-dimer could be useful in daily practice for the early diagnosis of acute mesenteric ischemia. Termedia Publishing House 2019-04-05 /pmc/articles/PMC7811331/ /pubmed/33488876 http://dx.doi.org/10.5114/aoms.2019.84225 Text en Copyright: © 2019 Termedia & Banach http://creativecommons.org/licenses/by-nc-sa/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) License, allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license. |
spellingShingle | Experimental Research Hot, Semih Egin, Seracettin Ilhan, Mehmet Bademler, Suleyman Dikker, Okan Aciksari, Kurtulus Kamali, Gulcin Seckin, Ismail Tanriverdi, Gamze Kamali, Sedat Guloglu, Recep The value of potassium, pH and D-dimer levels in early diagnosis of acute mesenteric ischemia: an experimental study on rats |
title | The value of potassium, pH and D-dimer levels in early diagnosis of acute mesenteric ischemia: an experimental study on rats |
title_full | The value of potassium, pH and D-dimer levels in early diagnosis of acute mesenteric ischemia: an experimental study on rats |
title_fullStr | The value of potassium, pH and D-dimer levels in early diagnosis of acute mesenteric ischemia: an experimental study on rats |
title_full_unstemmed | The value of potassium, pH and D-dimer levels in early diagnosis of acute mesenteric ischemia: an experimental study on rats |
title_short | The value of potassium, pH and D-dimer levels in early diagnosis of acute mesenteric ischemia: an experimental study on rats |
title_sort | value of potassium, ph and d-dimer levels in early diagnosis of acute mesenteric ischemia: an experimental study on rats |
topic | Experimental Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7811331/ https://www.ncbi.nlm.nih.gov/pubmed/33488876 http://dx.doi.org/10.5114/aoms.2019.84225 |
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