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Cross-species analysis of hepatic cytochrome P450 and transport protein expression

Most drugs and xenobiotics are metabolized in the liver. Amongst others, different cytochrome P450 (CYP) enzymes catalyze the metabolic conversion of foreign compounds, and various transport proteins are engaged in the excretion of metabolites from the hepatocytes. Inter-species and inter-individual...

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Detalles Bibliográficos
Autores principales:	Hammer, Helen, Schmidt, Felix, Marx-Stoelting, Philip, Pötz, Oliver, Braeuning, Albert
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2020
Materias:	Toxicokinetics and Metabolism
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7811513/ https://www.ncbi.nlm.nih.gov/pubmed/33150952 http://dx.doi.org/10.1007/s00204-020-02939-4

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