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Can adaptive clinical trials help to solve the productivity crisis of the pharmaceutical industry? - a scenario analysis
AIM: The productivity of pharmaceutical research and development (R&D) investments is declining due to high failure rates in clinical research. Recently, the US Food and Drug Administration (FDA) acknowledged that adaptive designs can make drug development more efficient and less costly. Our obj...
Autores principales: | Mahlich, Jörg, Bartol, Arne, Dheban, Srirangan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7811738/ https://www.ncbi.nlm.nih.gov/pubmed/33454837 http://dx.doi.org/10.1186/s13561-021-00302-6 |
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