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Αlpha 5 subunit-containing GABA(A) receptors in temporal lobe epilepsy with normal MRI
GABA(A) receptors containing the α5 subunit mediate tonic inhibition and are widely expressed in the limbic system. In animals, activation of α5-containing receptors impairs hippocampus-dependent memory. Temporal lobe epilepsy is associated with memory impairments related to neuron loss and other ch...
Autores principales: | McGinnity, Colm J, Riaño Barros, Daniela A, Hinz, Rainer, Myers, James F, Yaakub, Siti N, Thyssen, Charlotte, Heckemann, Rolf A, de Tisi, Jane, Duncan, John S, Sander, Josemir W, Lingford-Hughes, Anne, Koepp, Matthias J, Hammers, Alexander |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7811756/ https://www.ncbi.nlm.nih.gov/pubmed/33501420 http://dx.doi.org/10.1093/braincomms/fcaa190 |
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