Mitochondrial DNA in extracellular vesicles declines with age

The mitochondrial free radical theory of aging suggests that accumulating oxidative damage to mitochondria and mitochondrial DNA (mtDNA) plays a central role in aging. Circulating cell‐free mtDNA (ccf‐mtDNA) isolated from blood may be a biomarker of disease. Extracellular vesicles (EVs) are small (3...

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Detalles Bibliográficos
Autores principales: Lazo, Stephanie, Noren Hooten, Nicole, Green, Jamal, Eitan, Erez, Mode, Nicolle A., Liu, Qing‐Rong, Zonderman, Alan B., Ezike, Ngozi, Mattson, Mark P., Ghosh, Paritosh, Evans, Michele K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7811845/
https://www.ncbi.nlm.nih.gov/pubmed/33355987
http://dx.doi.org/10.1111/acel.13283

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7811845/
https://www.ncbi.nlm.nih.gov/pubmed/33355987
http://dx.doi.org/10.1111/acel.13283

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