Up‐regulation of cofilin‐1 in cell senescence associates with morphological change and p27(kip1)‐mediated growth delay

Morphological change is an explicit characteristic of cell senescence, but the underlying mechanisms remains to be addressed. Here, we demonstrated, after a survey of various actin‐binding proteins, that the post‐translational up‐regulation of cofilin‐1 was essential for the reduced rate of actin de...

Descripción completa

Detalles Bibliográficos
Autores principales: Tsai, Cheng‐Han, Chang, Chun‐Yuan, Lin, Bing‐Ze, Wu, Yu‐Lou, Wu, Meng‐Hsiu, Lin, Liang‐Tin, Huang, Wen‐Chien, Holz, Jonathan D., Sheu, Tzong‐Jen, Lee, Jhih‐Shian, Kitsis, Richard N., Tai, Pei‐Han, Lee, Yi‐Jang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7811848/
https://www.ncbi.nlm.nih.gov/pubmed/33336885
http://dx.doi.org/10.1111/acel.13288

Ejemplares similares

Ejemplares similares