Comparison of the Pharmacokinetics of RIPK1 Inhibitor GSK2982772 in Healthy Western and Japanese Subjects

BACKGROUND AND OBJECTIVES: GSK2982772 is an oral small-molecule RIPK1 inhibitor with potential therapeutic efficacy in immune-mediated inflammatory diseases (IMIDs). An inter-ethnic comparison of GSK2982772 pharmacokinetics was conducted based on data from Western (Study 1) and Japanese subjects (St...

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Detalles Bibliográficos
Autores principales: Tompson, Debra J., Davies, Carwyn, Scott, Nicola E., Cannons, Edward P., Kostapanos, Michalis, Gross, Annette S., Powell, Marcy, Ino, Hiroko, Shimamura, Ryutaro, Ogura, Hirofumi, Nagakubo, Takashi, Igarashi, Harue, Nakano, Atsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7811991/
https://www.ncbi.nlm.nih.gov/pubmed/33165774
http://dx.doi.org/10.1007/s13318-020-00652-2

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