Subcutaneous Delivery of High-Dose/Volume Biologics: Current Status and Prospect for Future Advancements

Subcutaneous (SC) delivery of biologics has traditionally been limited to fluid volumes of 1–2 mL, with recent increases to volumes of about 3 mL. This injection volume limitation poses challenges for high-dose biologics, as these formulations may also require increased solution concentration in man...

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Detalles Bibliográficos
Autores principales: Badkar, Advait V, Gandhi, Rajesh B, Davis, Shawn P, LaBarre, Michael J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7812053/
https://www.ncbi.nlm.nih.gov/pubmed/33469268
http://dx.doi.org/10.2147/DDDT.S287323

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7812053/
https://www.ncbi.nlm.nih.gov/pubmed/33469268
http://dx.doi.org/10.2147/DDDT.S287323

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