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Subcutaneous Delivery of High-Dose/Volume Biologics: Current Status and Prospect for Future Advancements
Subcutaneous (SC) delivery of biologics has traditionally been limited to fluid volumes of 1–2 mL, with recent increases to volumes of about 3 mL. This injection volume limitation poses challenges for high-dose biologics, as these formulations may also require increased solution concentration in man...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Dove
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7812053/ https://www.ncbi.nlm.nih.gov/pubmed/33469268 http://dx.doi.org/10.2147/DDDT.S287323 |