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Simultaneous Aerosol and Intramuscular Immunization with Influenza Vaccine Induces Powerful Protective Local T Cell and Systemic Antibody Immune Responses in Pigs
A vaccine providing both powerful Ab and cross-reactive T cell immune responses against influenza viruses would be beneficial for both humans and pigs. In this study, we evaluated i.m., aerosol (Aer), and simultaneous systemic and respiratory immunization (SIM) by both routes in Babraham pigs, using...
Autores principales: | Martini, Veronica, Paudyal, Basu, Chrun, Tiphany, McNee, Adam, Edmans, Matthew, Atangana Maze, Emmanuel, Clark, Beckie, Nunez, Alejandro, Dolton, Garry, Sewell, Andrew, Beverley, Peter, MacLoughlin, Ronan, Townsend, Alain, Tchilian, Elma |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AAI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7812058/ https://www.ncbi.nlm.nih.gov/pubmed/33328212 http://dx.doi.org/10.4049/jimmunol.2001086 |
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