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Alterations of DNA damage repair in cancer: from mechanisms to applications

DNA damage repair (DDR) pathways are essential to ensure the accurate transmission of genetic material. However, different endogenous and exogenous factors challenge genomic integrity. Mechanisms involved in the alterations of DDR pathways mainly include genetic inactivation and epigenetic mechanism...

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Detalles Bibliográficos
Autores principales:	Jiang, Minlin, Jia, Keyi, Wang, Lei, Li, Wei, Chen, Bin, Liu, Yu, Wang, Hao, Zhao, Sha, He, Yayi, Zhou, Caicun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AME Publishing Company 2020
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7812211/ https://www.ncbi.nlm.nih.gov/pubmed/33490197 http://dx.doi.org/10.21037/atm-20-2920

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