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COPD patients with chronic bronchitis and higher sputum eosinophil counts show increased type‐2 and PDE4 gene expression in sputum

Chronic obstructive pulmonary disease (COPD) patients with higher eosinophil counts are associated with increased clinical response to phosphodiesterase‐4‐inhibitors (PDE4i). However, the underlying inflammatory mechanisms associated with this increased response is not yet elucidated. This post hoc...

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Detalles Bibliográficos
Autores principales: Singh, Dave, Bassi, Michele, Balzano, Deborah, Lucci, Germano, Emirova, Aida, Anna Nandeuil, Marie, Jellema, Gera, Afolabi, Ebenezer K., Leaker, Brian, Kornmann, Oliver, Michael Beeh, Kai, Watz, Henrik, Govoni, Mirco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7812250/
https://www.ncbi.nlm.nih.gov/pubmed/33295083
http://dx.doi.org/10.1111/jcmm.16146