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The preventive and therapeutic effects of AAV1‐KLF4‐shRNA in cigarette smoke‐induced pulmonary hypertension

We found previously that KLF4 expression was up‐regulated in cultured rat and human pulmonary artery smooth muscle cells (PASMCs) exposed to cigarette smoke (CS) extract and in pulmonary artery from rats with pulmonary hypertension induced by CS. Here, we aim to investigate whether CS‐induced pulmon...

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Detalles Bibliográficos
Autores principales: Sun, Desheng, Ding, DanDan, Li, Qinghai, Xie, Min, Xu, Yongjian, Liu, Xiansheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7812256/
https://www.ncbi.nlm.nih.gov/pubmed/33342082
http://dx.doi.org/10.1111/jcmm.16194

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