Dysregulated YY1/PRMT5 axis promotes the progression and metastasis of laryngeal cancer by targeting Hippo pathway

Metastases lead to high mortality in laryngeal cancer, but the regulation of its underlying mechanisms remains elusive. We identified Protein arginine methyltransferase 5 (PRMT5) was significantly up‐regulated in laryngeal cancer tissues, which predicts poor patient prognosis. Functional assays demo...

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Detalles Bibliográficos
Autores principales: Wang, Nan, Wu, Di, Long, Qian, Yan, Yue, Chen, Xiaoqi, Zhao, Zheng, Yan, Honghong, Zhang, Xinrui, Xu, Meilan, Deng, Wuguo, Liu, Xuekui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7812261/
http://dx.doi.org/10.1111/jcmm.16156

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