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Combined inhibition of Ref‐1 and STAT3 leads to synergistic tumour inhibition in multiple cancers using 3D and in vivo tumour co‐culture models
With a plethora of molecularly targeted agents under investigation in cancer, a clear need exists to understand which pathways can be targeted simultaneously with multiple agents to elicit a maximal killing effect on the tumour. Combination therapy provides the most promise in difficult to treat can...
Autores principales: | Caston, Rachel A., Shah, Fenil, Starcher, Colton L., Wireman, Randall, Babb, Olivia, Grimard, Michelle, McGeown, Jack, Armstrong, Lee, Tong, Yan, Pili, Roberto, Rupert, Joseph, Zimmers, Teresa A., Elmi, Adily N., Pollok, Karen E., Motea, Edward A., Kelley, Mark R., Fishel, Melissa L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7812272/ https://www.ncbi.nlm.nih.gov/pubmed/33274592 http://dx.doi.org/10.1111/jcmm.16132 |
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