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Combined inhibition of Ref‐1 and STAT3 leads to synergistic tumour inhibition in multiple cancers using 3D and in vivo tumour co‐culture models

With a plethora of molecularly targeted agents under investigation in cancer, a clear need exists to understand which pathways can be targeted simultaneously with multiple agents to elicit a maximal killing effect on the tumour. Combination therapy provides the most promise in difficult to treat can...

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Detalles Bibliográficos
Autores principales: Caston, Rachel A., Shah, Fenil, Starcher, Colton L., Wireman, Randall, Babb, Olivia, Grimard, Michelle, McGeown, Jack, Armstrong, Lee, Tong, Yan, Pili, Roberto, Rupert, Joseph, Zimmers, Teresa A., Elmi, Adily N., Pollok, Karen E., Motea, Edward A., Kelley, Mark R., Fishel, Melissa L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7812272/
https://www.ncbi.nlm.nih.gov/pubmed/33274592
http://dx.doi.org/10.1111/jcmm.16132

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