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Neddylation inhibitor MLN4924 has anti‐HBV activity via modulating the ERK‐HNF1α‐C/EBPα‐HNF4α axis
Hepatitis B virus (HBV) infection is a major public health problem. The high levels of HBV DNA and HBsAg are positively associated with the development of secondary liver diseases, including hepatocellular carcinoma (HCC). Current treatment with nucleos(t)ide analogues mainly reduces viral DNA, but...
Autores principales: | Xie, Mingjie, Guo, Huiting, Lou, Guohua, Yao, Jiping, Liu, Yanning, Sun, Yi, Yang, Zhenggang, Zheng, Min |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7812279/ https://www.ncbi.nlm.nih.gov/pubmed/33263949 http://dx.doi.org/10.1111/jcmm.16137 |
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