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Ruxolitinib mitigates steroid‐refractory CRS during CAR T therapy
Cytokine release syndrome (CRS) and immune effector cell‐associated neurotoxicity are two major CAR T related toxicities. With the interventions of Tocilizumab and steroids, many patients can recover from severe CRS. However, some patients are refractory to steroids and develop life‐threatening cons...
Autores principales: | Pan, Jing, Deng, Biping, Ling, Zhuojun, Song, Weiliang, Xu, Jinlong, Duan, Jiajia, Wang, Zelin, Chang, Alex H., Feng, Xiaoming, Tan, Yue |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7812291/ https://www.ncbi.nlm.nih.gov/pubmed/33314568 http://dx.doi.org/10.1111/jcmm.16176 |
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