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Different mutant RUNX1 oncoproteins program alternate haematopoietic differentiation trajectories

Mutations of the haematopoietic master regulator RUNX1 are associated with acute myeloid leukaemia, familial platelet disorder and other haematological malignancies whose phenotypes and prognoses depend upon the class of the RUNX1 mutation. The biochemical behaviour of these oncoproteins and their a...

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Detalles Bibliográficos
Autores principales:	Kellaway, Sophie G, Keane, Peter, Edginton-White, Benjamin, Regha, Kakkad, Kennett, Ella, Bonifer, Constanze
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Life Science Alliance LLC 2021
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7812315/ https://www.ncbi.nlm.nih.gov/pubmed/33397648 http://dx.doi.org/10.26508/lsa.202000864

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