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Cyclin A2 localises in the cytoplasm at the S/G2 transition to activate PLK1

Cyclin A2 is a key regulator of the cell cycle, implicated both in DNA replication and mitotic entry. Cyclin A2 participates in feedback loops that activate mitotic kinases in G2 phase, but why active Cyclin A2-CDK2 during the S phase does not trigger mitotic kinase activation remains unclear. Here,...

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Detalles Bibliográficos
Autores principales:	Silva Cascales, Helena, Burdova, Kamila, Middleton, Anna, Kuzin, Vladislav, Müllers, Erik, Stoy, Henriette, Baranello, Laura, Macurek, Libor, Lindqvist, Arne
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Life Science Alliance LLC 2021
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7812317/ https://www.ncbi.nlm.nih.gov/pubmed/33402344 http://dx.doi.org/10.26508/lsa.202000980

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