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B.2.16 is a non-lethal modifier of the Dark(82) mosaic eye phenotype in Drosophila melanogaster

Genetic screens have been used to identify genes involved in the regulation of different biological processes. We identified growth mutants in a Flp/FRT screen using the Drosophila melanogaster eye to identify conditional regulators of cell growth and cell division. One mutant identified from this s...

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Autores principales: Vrailas-Mortimer, Alysia D, Aggarwal, Nitish, Ahmed, Neha N, Alberts, Ian M, Alhawasli, Masa, Aljerdi, Ibrahim A, Allen, Brooke M, Alnajar, Ahmad M, Anderson, Michael A, Armstong, Ryan, Avery, Chace C, Avila, Eric J, Baker, Tyra N, Basardeh, Soolmaz, Bates, Natasha A, Beidas, Farrah N, Bosler, Ashton C, Brewer, Deja M, Buenaventura, Ryan S, Burrell, Natalie JL, Cabrera-Lopez, Alyn P, Cervantes-Gonzalez, Amairani B, Cezar, Raymond P, Coronel, Joselyn, Croslyn, Corinne, Damery, Konnor R, Diaz-Alavez, Lucero, Dixit, Nupur P, Duarte, Dilcia L, Emke, Amanda R, English, Katherine, Eshun, Audrey A, Esterly, Samuel R, Estrada, Arnold J, Feng, Mark, Freund, Meghan M, Garcia, Niko, Ghotra, Charandeep S, Ghyasi, Haddia, Hale, Christa SA, Hulsman, Luci, Jamerson, Lindsey, Jones, Austin K, Kuczynski, Madeline, Lacey-Kennedy, Takailah N, Lee, Mindy J, Mahjoub, Tala, Mersinger, Molly C, Muckerheide, Alyssa D, Myers, David W, Nielsen, Karen, Nosowicz, Paul J, Nunez, Jacinda A, Ortiz, Amy C, Patel, Tulsi T, Perry, Natalie N, Poser, W Storm A, Puga, Deisy M, Quam, Cathrine, Quintana-Lopez, Paulina, Rennerfeldt, Piper, Reyes, Nicholas M, Rines, Ian G, Roberts, Cally, Robinson, Daniel B, Rossa, Kalina M, Ruhlmann, Gloria J, Schmidt, Jeremy, Sherwood, John R, Shonoda, Dimyana H, Soellner, Hannah, Torrez, Juan C, Velide, Mayukah, Weinzapfel, Zachary, Ward, Alisa C, Bieser, Kayla L, Merkle, Julie A, Stamm, Joyce C, Tillett, Richard L, Kagey, Jacob D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Caltech Library 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7812380/
https://www.ncbi.nlm.nih.gov/pubmed/33474526
http://dx.doi.org/10.17912/micropub.biology.000359
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author Vrailas-Mortimer, Alysia D
Aggarwal, Nitish
Ahmed, Neha N
Alberts, Ian M
Alhawasli, Masa
Aljerdi, Ibrahim A
Allen, Brooke M
Alnajar, Ahmad M
Anderson, Michael A
Armstong, Ryan
Avery, Chace C
Avila, Eric J
Baker, Tyra N
Basardeh, Soolmaz
Bates, Natasha A
Beidas, Farrah N
Bosler, Ashton C
Brewer, Deja M
Buenaventura, Ryan S
Burrell, Natalie JL
Cabrera-Lopez, Alyn P
Cervantes-Gonzalez, Amairani B
Cezar, Raymond P
Coronel, Joselyn
Croslyn, Corinne
Damery, Konnor R
Diaz-Alavez, Lucero
Dixit, Nupur P
Duarte, Dilcia L
Emke, Amanda R
English, Katherine
Eshun, Audrey A
Esterly, Samuel R
Estrada, Arnold J
Feng, Mark
Freund, Meghan M
Garcia, Niko
Ghotra, Charandeep S
Ghyasi, Haddia
Hale, Christa SA
Hulsman, Luci
Jamerson, Lindsey
Jones, Austin K
Kuczynski, Madeline
Lacey-Kennedy, Takailah N
Lee, Mindy J
Mahjoub, Tala
Mersinger, Molly C
Muckerheide, Alyssa D
Myers, David W
Nielsen, Karen
Nosowicz, Paul J
Nunez, Jacinda A
Ortiz, Amy C
Patel, Tulsi T
Perry, Natalie N
Poser, W Storm A
Puga, Deisy M
Quam, Cathrine
Quintana-Lopez, Paulina
Rennerfeldt, Piper
Reyes, Nicholas M
Rines, Ian G
Roberts, Cally
Robinson, Daniel B
Rossa, Kalina M
Ruhlmann, Gloria J
Schmidt, Jeremy
Sherwood, John R
Shonoda, Dimyana H
Soellner, Hannah
Torrez, Juan C
Velide, Mayukah
Weinzapfel, Zachary
Ward, Alisa C
Bieser, Kayla L
Merkle, Julie A
Stamm, Joyce C
Tillett, Richard L
Kagey, Jacob D
author_facet Vrailas-Mortimer, Alysia D
Aggarwal, Nitish
Ahmed, Neha N
Alberts, Ian M
Alhawasli, Masa
Aljerdi, Ibrahim A
Allen, Brooke M
Alnajar, Ahmad M
Anderson, Michael A
Armstong, Ryan
Avery, Chace C
Avila, Eric J
Baker, Tyra N
Basardeh, Soolmaz
Bates, Natasha A
Beidas, Farrah N
Bosler, Ashton C
Brewer, Deja M
Buenaventura, Ryan S
Burrell, Natalie JL
Cabrera-Lopez, Alyn P
Cervantes-Gonzalez, Amairani B
Cezar, Raymond P
Coronel, Joselyn
Croslyn, Corinne
Damery, Konnor R
Diaz-Alavez, Lucero
Dixit, Nupur P
Duarte, Dilcia L
Emke, Amanda R
English, Katherine
Eshun, Audrey A
Esterly, Samuel R
Estrada, Arnold J
Feng, Mark
Freund, Meghan M
Garcia, Niko
Ghotra, Charandeep S
Ghyasi, Haddia
Hale, Christa SA
Hulsman, Luci
Jamerson, Lindsey
Jones, Austin K
Kuczynski, Madeline
Lacey-Kennedy, Takailah N
Lee, Mindy J
Mahjoub, Tala
Mersinger, Molly C
Muckerheide, Alyssa D
Myers, David W
Nielsen, Karen
Nosowicz, Paul J
Nunez, Jacinda A
Ortiz, Amy C
Patel, Tulsi T
Perry, Natalie N
Poser, W Storm A
Puga, Deisy M
Quam, Cathrine
Quintana-Lopez, Paulina
Rennerfeldt, Piper
Reyes, Nicholas M
Rines, Ian G
Roberts, Cally
Robinson, Daniel B
Rossa, Kalina M
Ruhlmann, Gloria J
Schmidt, Jeremy
Sherwood, John R
Shonoda, Dimyana H
Soellner, Hannah
Torrez, Juan C
Velide, Mayukah
Weinzapfel, Zachary
Ward, Alisa C
Bieser, Kayla L
Merkle, Julie A
Stamm, Joyce C
Tillett, Richard L
Kagey, Jacob D
author_sort Vrailas-Mortimer, Alysia D
collection PubMed
description Genetic screens have been used to identify genes involved in the regulation of different biological processes. We identified growth mutants in a Flp/FRT screen using the Drosophila melanogaster eye to identify conditional regulators of cell growth and cell division. One mutant identified from this screen, B.2.16, was mapped and characterized by researchers in undergraduate genetics labs as part of the Fly-CURE. We find that B.2.16 is a non-lethal genetic modifier of the Dark(82) mosaic eye phenotype.
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spelling pubmed-78123802021-01-19 B.2.16 is a non-lethal modifier of the Dark(82) mosaic eye phenotype in Drosophila melanogaster Vrailas-Mortimer, Alysia D Aggarwal, Nitish Ahmed, Neha N Alberts, Ian M Alhawasli, Masa Aljerdi, Ibrahim A Allen, Brooke M Alnajar, Ahmad M Anderson, Michael A Armstong, Ryan Avery, Chace C Avila, Eric J Baker, Tyra N Basardeh, Soolmaz Bates, Natasha A Beidas, Farrah N Bosler, Ashton C Brewer, Deja M Buenaventura, Ryan S Burrell, Natalie JL Cabrera-Lopez, Alyn P Cervantes-Gonzalez, Amairani B Cezar, Raymond P Coronel, Joselyn Croslyn, Corinne Damery, Konnor R Diaz-Alavez, Lucero Dixit, Nupur P Duarte, Dilcia L Emke, Amanda R English, Katherine Eshun, Audrey A Esterly, Samuel R Estrada, Arnold J Feng, Mark Freund, Meghan M Garcia, Niko Ghotra, Charandeep S Ghyasi, Haddia Hale, Christa SA Hulsman, Luci Jamerson, Lindsey Jones, Austin K Kuczynski, Madeline Lacey-Kennedy, Takailah N Lee, Mindy J Mahjoub, Tala Mersinger, Molly C Muckerheide, Alyssa D Myers, David W Nielsen, Karen Nosowicz, Paul J Nunez, Jacinda A Ortiz, Amy C Patel, Tulsi T Perry, Natalie N Poser, W Storm A Puga, Deisy M Quam, Cathrine Quintana-Lopez, Paulina Rennerfeldt, Piper Reyes, Nicholas M Rines, Ian G Roberts, Cally Robinson, Daniel B Rossa, Kalina M Ruhlmann, Gloria J Schmidt, Jeremy Sherwood, John R Shonoda, Dimyana H Soellner, Hannah Torrez, Juan C Velide, Mayukah Weinzapfel, Zachary Ward, Alisa C Bieser, Kayla L Merkle, Julie A Stamm, Joyce C Tillett, Richard L Kagey, Jacob D MicroPubl Biol New Finding Genetic screens have been used to identify genes involved in the regulation of different biological processes. We identified growth mutants in a Flp/FRT screen using the Drosophila melanogaster eye to identify conditional regulators of cell growth and cell division. One mutant identified from this screen, B.2.16, was mapped and characterized by researchers in undergraduate genetics labs as part of the Fly-CURE. We find that B.2.16 is a non-lethal genetic modifier of the Dark(82) mosaic eye phenotype. Caltech Library 2021-01-18 /pmc/articles/PMC7812380/ /pubmed/33474526 http://dx.doi.org/10.17912/micropub.biology.000359 Text en Copyright: © 2021 by the authors https://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle New Finding
Vrailas-Mortimer, Alysia D
Aggarwal, Nitish
Ahmed, Neha N
Alberts, Ian M
Alhawasli, Masa
Aljerdi, Ibrahim A
Allen, Brooke M
Alnajar, Ahmad M
Anderson, Michael A
Armstong, Ryan
Avery, Chace C
Avila, Eric J
Baker, Tyra N
Basardeh, Soolmaz
Bates, Natasha A
Beidas, Farrah N
Bosler, Ashton C
Brewer, Deja M
Buenaventura, Ryan S
Burrell, Natalie JL
Cabrera-Lopez, Alyn P
Cervantes-Gonzalez, Amairani B
Cezar, Raymond P
Coronel, Joselyn
Croslyn, Corinne
Damery, Konnor R
Diaz-Alavez, Lucero
Dixit, Nupur P
Duarte, Dilcia L
Emke, Amanda R
English, Katherine
Eshun, Audrey A
Esterly, Samuel R
Estrada, Arnold J
Feng, Mark
Freund, Meghan M
Garcia, Niko
Ghotra, Charandeep S
Ghyasi, Haddia
Hale, Christa SA
Hulsman, Luci
Jamerson, Lindsey
Jones, Austin K
Kuczynski, Madeline
Lacey-Kennedy, Takailah N
Lee, Mindy J
Mahjoub, Tala
Mersinger, Molly C
Muckerheide, Alyssa D
Myers, David W
Nielsen, Karen
Nosowicz, Paul J
Nunez, Jacinda A
Ortiz, Amy C
Patel, Tulsi T
Perry, Natalie N
Poser, W Storm A
Puga, Deisy M
Quam, Cathrine
Quintana-Lopez, Paulina
Rennerfeldt, Piper
Reyes, Nicholas M
Rines, Ian G
Roberts, Cally
Robinson, Daniel B
Rossa, Kalina M
Ruhlmann, Gloria J
Schmidt, Jeremy
Sherwood, John R
Shonoda, Dimyana H
Soellner, Hannah
Torrez, Juan C
Velide, Mayukah
Weinzapfel, Zachary
Ward, Alisa C
Bieser, Kayla L
Merkle, Julie A
Stamm, Joyce C
Tillett, Richard L
Kagey, Jacob D
B.2.16 is a non-lethal modifier of the Dark(82) mosaic eye phenotype in Drosophila melanogaster
title B.2.16 is a non-lethal modifier of the Dark(82) mosaic eye phenotype in Drosophila melanogaster
title_full B.2.16 is a non-lethal modifier of the Dark(82) mosaic eye phenotype in Drosophila melanogaster
title_fullStr B.2.16 is a non-lethal modifier of the Dark(82) mosaic eye phenotype in Drosophila melanogaster
title_full_unstemmed B.2.16 is a non-lethal modifier of the Dark(82) mosaic eye phenotype in Drosophila melanogaster
title_short B.2.16 is a non-lethal modifier of the Dark(82) mosaic eye phenotype in Drosophila melanogaster
title_sort b.2.16 is a non-lethal modifier of the dark(82) mosaic eye phenotype in drosophila melanogaster
topic New Finding
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7812380/
https://www.ncbi.nlm.nih.gov/pubmed/33474526
http://dx.doi.org/10.17912/micropub.biology.000359
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