Cargando…

IOX1 protects from TGF-β induced fibrosis in LX-2 cells via the regulation of extracellular matrix protein expression

The aim of the present study was to investigate the effect of the histone H3K9 demethylase inhibitor, IOX1, on the mechanism of hepatic fibrosis in TGF-β-induced human hepatic stellate LX-2 cells. Cellular proliferation, apoptosis, histone H3K9 dimethylation (H3K9me2), protein expression of extracel...

Descripción completa

Detalles Bibliográficos
Autores principales: Tian, Tian, Xie, Rujia, Ding, Kaize, Han, Bing, Yang, Qin, Yang, Xue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7812578/
https://www.ncbi.nlm.nih.gov/pubmed/33488789
http://dx.doi.org/10.3892/etm.2021.9611