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A study on episodic memory reconsolidation that tells us more about consolidation
Awake quiescence immediately after encoding is conducive to episodic memory consolidation. Retrieval can render episodic memories labile again, but reconsolidation can modify and restrengthen them. It remained unknown whether awake quiescence after retrieval supports episodic memory reconsolidation....
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7812862/ https://www.ncbi.nlm.nih.gov/pubmed/33452111 http://dx.doi.org/10.1101/lm.052274.120 |
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author | Craig, Michael Knowles, Christopher Hill, Stephanie Dewar, Michaela |
author_facet | Craig, Michael Knowles, Christopher Hill, Stephanie Dewar, Michaela |
author_sort | Craig, Michael |
collection | PubMed |
description | Awake quiescence immediately after encoding is conducive to episodic memory consolidation. Retrieval can render episodic memories labile again, but reconsolidation can modify and restrengthen them. It remained unknown whether awake quiescence after retrieval supports episodic memory reconsolidation. We sought to examine this question via an object-location memory paradigm. We failed to probe the effect of quiescence on reconsolidation, but we did observe an unforeseen “delayed” effect of quiescence on consolidation. Our findings reveal that the beneficial effect of quiescence on episodic memory consolidation is not restricted to immediately following encoding but can be achieved at a delayed stage and even following a period of task engagement. |
format | Online Article Text |
id | pubmed-7812862 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Cold Spring Harbor Laboratory Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-78128622022-02-01 A study on episodic memory reconsolidation that tells us more about consolidation Craig, Michael Knowles, Christopher Hill, Stephanie Dewar, Michaela Learn Mem Brief Communication Awake quiescence immediately after encoding is conducive to episodic memory consolidation. Retrieval can render episodic memories labile again, but reconsolidation can modify and restrengthen them. It remained unknown whether awake quiescence after retrieval supports episodic memory reconsolidation. We sought to examine this question via an object-location memory paradigm. We failed to probe the effect of quiescence on reconsolidation, but we did observe an unforeseen “delayed” effect of quiescence on consolidation. Our findings reveal that the beneficial effect of quiescence on episodic memory consolidation is not restricted to immediately following encoding but can be achieved at a delayed stage and even following a period of task engagement. Cold Spring Harbor Laboratory Press 2021-02 /pmc/articles/PMC7812862/ /pubmed/33452111 http://dx.doi.org/10.1101/lm.052274.120 Text en © 2021 Craig et al.; Published by Cold Spring Harbor Laboratory Press http://creativecommons.org/licenses/by-nc/4.0/ This article is distributed exclusively by Cold Spring Harbor Laboratory Press for the first 12 months after the full-issue publication date (see http://learnmem.cshlp.org/site/misc/terms.xhtml). After 12 months, it is available under a Creative Commons License (Attribution-NonCommercial 4.0 International), as described at http://creativecommons.org/licenses/by-nc/4.0/. |
spellingShingle | Brief Communication Craig, Michael Knowles, Christopher Hill, Stephanie Dewar, Michaela A study on episodic memory reconsolidation that tells us more about consolidation |
title | A study on episodic memory reconsolidation that tells us more about consolidation |
title_full | A study on episodic memory reconsolidation that tells us more about consolidation |
title_fullStr | A study on episodic memory reconsolidation that tells us more about consolidation |
title_full_unstemmed | A study on episodic memory reconsolidation that tells us more about consolidation |
title_short | A study on episodic memory reconsolidation that tells us more about consolidation |
title_sort | study on episodic memory reconsolidation that tells us more about consolidation |
topic | Brief Communication |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7812862/ https://www.ncbi.nlm.nih.gov/pubmed/33452111 http://dx.doi.org/10.1101/lm.052274.120 |
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