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A study on episodic memory reconsolidation that tells us more about consolidation

Awake quiescence immediately after encoding is conducive to episodic memory consolidation. Retrieval can render episodic memories labile again, but reconsolidation can modify and restrengthen them. It remained unknown whether awake quiescence after retrieval supports episodic memory reconsolidation....

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Detalles Bibliográficos
Autores principales: Craig, Michael, Knowles, Christopher, Hill, Stephanie, Dewar, Michaela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7812862/
https://www.ncbi.nlm.nih.gov/pubmed/33452111
http://dx.doi.org/10.1101/lm.052274.120
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author Craig, Michael
Knowles, Christopher
Hill, Stephanie
Dewar, Michaela
author_facet Craig, Michael
Knowles, Christopher
Hill, Stephanie
Dewar, Michaela
author_sort Craig, Michael
collection PubMed
description Awake quiescence immediately after encoding is conducive to episodic memory consolidation. Retrieval can render episodic memories labile again, but reconsolidation can modify and restrengthen them. It remained unknown whether awake quiescence after retrieval supports episodic memory reconsolidation. We sought to examine this question via an object-location memory paradigm. We failed to probe the effect of quiescence on reconsolidation, but we did observe an unforeseen “delayed” effect of quiescence on consolidation. Our findings reveal that the beneficial effect of quiescence on episodic memory consolidation is not restricted to immediately following encoding but can be achieved at a delayed stage and even following a period of task engagement.
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spelling pubmed-78128622022-02-01 A study on episodic memory reconsolidation that tells us more about consolidation Craig, Michael Knowles, Christopher Hill, Stephanie Dewar, Michaela Learn Mem Brief Communication Awake quiescence immediately after encoding is conducive to episodic memory consolidation. Retrieval can render episodic memories labile again, but reconsolidation can modify and restrengthen them. It remained unknown whether awake quiescence after retrieval supports episodic memory reconsolidation. We sought to examine this question via an object-location memory paradigm. We failed to probe the effect of quiescence on reconsolidation, but we did observe an unforeseen “delayed” effect of quiescence on consolidation. Our findings reveal that the beneficial effect of quiescence on episodic memory consolidation is not restricted to immediately following encoding but can be achieved at a delayed stage and even following a period of task engagement. Cold Spring Harbor Laboratory Press 2021-02 /pmc/articles/PMC7812862/ /pubmed/33452111 http://dx.doi.org/10.1101/lm.052274.120 Text en © 2021 Craig et al.; Published by Cold Spring Harbor Laboratory Press http://creativecommons.org/licenses/by-nc/4.0/ This article is distributed exclusively by Cold Spring Harbor Laboratory Press for the first 12 months after the full-issue publication date (see http://learnmem.cshlp.org/site/misc/terms.xhtml). After 12 months, it is available under a Creative Commons License (Attribution-NonCommercial 4.0 International), as described at http://creativecommons.org/licenses/by-nc/4.0/.
spellingShingle Brief Communication
Craig, Michael
Knowles, Christopher
Hill, Stephanie
Dewar, Michaela
A study on episodic memory reconsolidation that tells us more about consolidation
title A study on episodic memory reconsolidation that tells us more about consolidation
title_full A study on episodic memory reconsolidation that tells us more about consolidation
title_fullStr A study on episodic memory reconsolidation that tells us more about consolidation
title_full_unstemmed A study on episodic memory reconsolidation that tells us more about consolidation
title_short A study on episodic memory reconsolidation that tells us more about consolidation
title_sort study on episodic memory reconsolidation that tells us more about consolidation
topic Brief Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7812862/
https://www.ncbi.nlm.nih.gov/pubmed/33452111
http://dx.doi.org/10.1101/lm.052274.120
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