Cargando…
Posttranscriptional modifications at the 37th position in the anticodon stem–loop of tRNA: structural insights from MD simulations
Transfer RNA (tRNA) is the most diversely modified RNA. Although the strictly conserved purine position 37 in the anticodon stem–loop undergoes modifications that are phylogenetically distributed, we do not yet fully understand the roles of these modifications. Therefore, molecular dynamics simulati...
Autores principales: | Seelam Prabhakar, Preethi, Takyi, Nathania A., Wetmore, Stacey D. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7812866/ https://www.ncbi.nlm.nih.gov/pubmed/33214333 http://dx.doi.org/10.1261/rna.078097.120 |
Ejemplares similares
-
“Superwobbling” and tRNA-34 Wobble and tRNA-37 Anticodon Loop Modifications in Evolution and Devolution of the Genetic Code
por: Lei, Lei, et al.
Publicado: (2022) -
A rationale for tRNA modification circuits in the anticodon loop
por: Han, Lu, et al.
Publicado: (2018) -
Impact of the Position of the Chemically Modified 5-Furyl-2′-Deoxyuridine Nucleoside on the Thrombin DNA Aptamer–Protein Complex: Structural Insights into Aptamer Response from MD Simulations
por: Seelam Prabhakar, Preethi, et al.
Publicado: (2019) -
Conservation of an intricate circuit for crucial modifications of the tRNA(Phe) anticodon loop in eukaryotes
por: Guy, Michael P., et al.
Publicado: (2015) -
tRNA anticodon loop modifications ensure protein homeostasis and cell morphogenesis in yeast
por: Klassen, Roland, et al.
Publicado: (2016)