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An open interface in the pre-80S ribosome coordinated by ribosome assembly factors Tsr1 and Dim1 enables temporal regulation of Fap7

During their maturation, nascent 40S subunits enter a translation-like quality control cycle, where they are joined by mature 60S subunits to form 80S-like ribosomes. While these assembly intermediates are essential for maturation and quality control, how they form, and how their structure promotes...

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Detalles Bibliográficos
Autores principales: Rai, Jay, Parker, Melissa D., Huang, Haina, Choy, Stefan, Ghalei, Homa, Johnson, Matthew C., Karbstein, Katrin, Stroupe, M. Elizabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7812869/
https://www.ncbi.nlm.nih.gov/pubmed/33219089
http://dx.doi.org/10.1261/rna.077610.120