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An Arf/Rab cascade controls the growth and invasiveness of glioblastoma

Glioblastoma is the most common and deadly malignant brain cancer. We now demonstrate that loss of function of the endosomal GTPase Rab35 in human brain tumor initiating cells (BTICs) increases glioblastoma growth and decreases animal survival following BTIC implantation in mouse brains. Mechanistic...

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Detalles Bibliográficos
Autores principales:	Kulasekaran, Gopinath, Chaineau, Mathilde, Piscopo, Valerio Emilio Crescenzo, Verginelli, Federica, Fotouhi, Maryam, Girard, Martine, Tang, Yeman, Dali, Rola, Lo, Rita, Stifani, Stefano, McPherson, Peter S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7812876/ https://www.ncbi.nlm.nih.gov/pubmed/33443570 http://dx.doi.org/10.1083/jcb.202004229

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