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Avoidance of deep anesthesia and artificial airways in 1000 neonates and infants using regional anesthesia: A retrospective observational analysis

BACKGROUND AND AIMS: Current concerns related to the anesthetic neurotoxicity have brought a renewed interest in regional anesthesia. Regional anesthesia reduces the need for opioids and inhalational anesthetics. The immaturity of the neonatal and infant nervous system may render them more prone to...

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Autores principales: Ponde, Vrushali C., Chavan, Dilip N., Desai, Ankit P., Gursale, Anuya A., Bedekar, Vinit V., Puranik, Kiran A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7812947/
https://www.ncbi.nlm.nih.gov/pubmed/33487908
http://dx.doi.org/10.4103/joacp.JOACP_200_17
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author Ponde, Vrushali C.
Chavan, Dilip N.
Desai, Ankit P.
Gursale, Anuya A.
Bedekar, Vinit V.
Puranik, Kiran A.
author_facet Ponde, Vrushali C.
Chavan, Dilip N.
Desai, Ankit P.
Gursale, Anuya A.
Bedekar, Vinit V.
Puranik, Kiran A.
author_sort Ponde, Vrushali C.
collection PubMed
description BACKGROUND AND AIMS: Current concerns related to the anesthetic neurotoxicity have brought a renewed interest in regional anesthesia. Regional anesthesia reduces the need for opioids and inhalational anesthetics. The immaturity of the neonatal and infant nervous system may render them more prone to neurotoxicity. We describe our technique of anesthesia, which minimizes the exposure to general anesthetics and reduces airway instrumentation because the operability is rendered by the regional block. MATERIAL AND METHODS: This was a retrospective case series of neonates and infants undergoing common surface surgeries. We describe our technique of anesthesia where regional blocks are the mainstay. We also put up the data pertaining to block effectiveness, technique, end-tidal sevoflurane concentration and complications. RESULTS: One thousand patients, including neonates and infants, received central and peripheral nerve blockade. The failure rate in upper extremity blocks 0% without complications. 86.12% were given under ultrasonography (USG) guidance and 13.89% were given with peripheral nerve stimulation. The failure rate of sciatic block single shot and continuous was 0%. 92.53% were given with USG guidance while 7.46% received sciatic with nerve stimulation technique. Failure rate of caudal epidural block was 0. 78% requiring a rescue analgesic, 1.4% had blood in the needle. Out of the caudals, 33.33% were done with USG guidance and 66.67% blocks were given with traditional techniques. Out of the 322 penile + ring blocks given by traditional method, 1 block failed requiring rescue analgesics. The mean sevoflurane concentration was 1.2 +/- 0.32. CONCLUSION: It is feasible to conduct surface surgeries in the most vulnerable population such as neonates and infants under regional anesthesia without intubation and airway instrumentation.
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spelling pubmed-78129472021-01-22 Avoidance of deep anesthesia and artificial airways in 1000 neonates and infants using regional anesthesia: A retrospective observational analysis Ponde, Vrushali C. Chavan, Dilip N. Desai, Ankit P. Gursale, Anuya A. Bedekar, Vinit V. Puranik, Kiran A. J Anaesthesiol Clin Pharmacol Original Article BACKGROUND AND AIMS: Current concerns related to the anesthetic neurotoxicity have brought a renewed interest in regional anesthesia. Regional anesthesia reduces the need for opioids and inhalational anesthetics. The immaturity of the neonatal and infant nervous system may render them more prone to neurotoxicity. We describe our technique of anesthesia, which minimizes the exposure to general anesthetics and reduces airway instrumentation because the operability is rendered by the regional block. MATERIAL AND METHODS: This was a retrospective case series of neonates and infants undergoing common surface surgeries. We describe our technique of anesthesia where regional blocks are the mainstay. We also put up the data pertaining to block effectiveness, technique, end-tidal sevoflurane concentration and complications. RESULTS: One thousand patients, including neonates and infants, received central and peripheral nerve blockade. The failure rate in upper extremity blocks 0% without complications. 86.12% were given under ultrasonography (USG) guidance and 13.89% were given with peripheral nerve stimulation. The failure rate of sciatic block single shot and continuous was 0%. 92.53% were given with USG guidance while 7.46% received sciatic with nerve stimulation technique. Failure rate of caudal epidural block was 0. 78% requiring a rescue analgesic, 1.4% had blood in the needle. Out of the caudals, 33.33% were done with USG guidance and 66.67% blocks were given with traditional techniques. Out of the 322 penile + ring blocks given by traditional method, 1 block failed requiring rescue analgesics. The mean sevoflurane concentration was 1.2 +/- 0.32. CONCLUSION: It is feasible to conduct surface surgeries in the most vulnerable population such as neonates and infants under regional anesthesia without intubation and airway instrumentation. Wolters Kluwer - Medknow 2020 2020-09-28 /pmc/articles/PMC7812947/ /pubmed/33487908 http://dx.doi.org/10.4103/joacp.JOACP_200_17 Text en Copyright: © 2020 Journal of Anaesthesiology Clinical Pharmacology http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Ponde, Vrushali C.
Chavan, Dilip N.
Desai, Ankit P.
Gursale, Anuya A.
Bedekar, Vinit V.
Puranik, Kiran A.
Avoidance of deep anesthesia and artificial airways in 1000 neonates and infants using regional anesthesia: A retrospective observational analysis
title Avoidance of deep anesthesia and artificial airways in 1000 neonates and infants using regional anesthesia: A retrospective observational analysis
title_full Avoidance of deep anesthesia and artificial airways in 1000 neonates and infants using regional anesthesia: A retrospective observational analysis
title_fullStr Avoidance of deep anesthesia and artificial airways in 1000 neonates and infants using regional anesthesia: A retrospective observational analysis
title_full_unstemmed Avoidance of deep anesthesia and artificial airways in 1000 neonates and infants using regional anesthesia: A retrospective observational analysis
title_short Avoidance of deep anesthesia and artificial airways in 1000 neonates and infants using regional anesthesia: A retrospective observational analysis
title_sort avoidance of deep anesthesia and artificial airways in 1000 neonates and infants using regional anesthesia: a retrospective observational analysis
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7812947/
https://www.ncbi.nlm.nih.gov/pubmed/33487908
http://dx.doi.org/10.4103/joacp.JOACP_200_17
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