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Hypusination Orchestrates the Antimicrobial Response of Macrophages

Innate responses of myeloid cells defend against pathogenic bacteria via inducible effectors. Deoxyhypusine synthase (DHPS) catalyzes the transfer of the N-moiety of spermidine to the lysine-50 residue of eukaryotic translation initiation factor 5A (EIF5A) to form the amino acid hypusine. Hypusinate...

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Detalles Bibliográficos
Autores principales:	Gobert, Alain P., Finley, Jordan L., Latour, Yvonne L., Asim, Mohammad, Smith, Thaddeus M., Verriere, Thomas G., Barry, Daniel P., Allaman, Margaret M., Delagado, Alberto G., Rose, Kristie L., Calcutt, M. Wade, Schey, Kevin L., Sierra, Johanna C., Piazuelo, M. Blanca, Mirmira, Raghavendra G., Wilson, Keith T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7812972/ https://www.ncbi.nlm.nih.gov/pubmed/33326776 http://dx.doi.org/10.1016/j.celrep.2020.108510

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