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Catastrophic intracranial hemorrhage associated with eosinophilic granulomatous polyangiitis in a patient after Fontan operation
A 29‐year‐old man after the Fontan operation had a catastrophic intracranial hemorrhage associated with eosinophilic granulomatous polyangiitis. Despite combination therapy with cyclophosphamide and methylprednisolone, he was dead at 6 months after the onset. The clinical course was worse owing to u...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7813104/ https://www.ncbi.nlm.nih.gov/pubmed/33489213 http://dx.doi.org/10.1002/ccr3.3579 |
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author | Ezaki, Hiroki Muneuchi, Jun Imamoto, Naoyuki |
author_facet | Ezaki, Hiroki Muneuchi, Jun Imamoto, Naoyuki |
author_sort | Ezaki, Hiroki |
collection | PubMed |
description | A 29‐year‐old man after the Fontan operation had a catastrophic intracranial hemorrhage associated with eosinophilic granulomatous polyangiitis. Despite combination therapy with cyclophosphamide and methylprednisolone, he was dead at 6 months after the onset. The clinical course was worse owing to underlying coagulopathy and endothelial dysfunction associated with congenital heart disease. Key Clnical Massage The majority of patients with complex congenital heart disease survive into adulthood. Potential endothelial dysfunction and coagulopathy can attribute to unexpected clinical manifestations of other extracardiac disease among them. |
format | Online Article Text |
id | pubmed-7813104 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-78131042021-01-22 Catastrophic intracranial hemorrhage associated with eosinophilic granulomatous polyangiitis in a patient after Fontan operation Ezaki, Hiroki Muneuchi, Jun Imamoto, Naoyuki Clin Case Rep Case Reports A 29‐year‐old man after the Fontan operation had a catastrophic intracranial hemorrhage associated with eosinophilic granulomatous polyangiitis. Despite combination therapy with cyclophosphamide and methylprednisolone, he was dead at 6 months after the onset. The clinical course was worse owing to underlying coagulopathy and endothelial dysfunction associated with congenital heart disease. Key Clnical Massage The majority of patients with complex congenital heart disease survive into adulthood. Potential endothelial dysfunction and coagulopathy can attribute to unexpected clinical manifestations of other extracardiac disease among them. John Wiley and Sons Inc. 2020-12-11 /pmc/articles/PMC7813104/ /pubmed/33489213 http://dx.doi.org/10.1002/ccr3.3579 Text en © 2020 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. |
spellingShingle | Case Reports Ezaki, Hiroki Muneuchi, Jun Imamoto, Naoyuki Catastrophic intracranial hemorrhage associated with eosinophilic granulomatous polyangiitis in a patient after Fontan operation |
title | Catastrophic intracranial hemorrhage associated with eosinophilic granulomatous polyangiitis in a patient after Fontan operation |
title_full | Catastrophic intracranial hemorrhage associated with eosinophilic granulomatous polyangiitis in a patient after Fontan operation |
title_fullStr | Catastrophic intracranial hemorrhage associated with eosinophilic granulomatous polyangiitis in a patient after Fontan operation |
title_full_unstemmed | Catastrophic intracranial hemorrhage associated with eosinophilic granulomatous polyangiitis in a patient after Fontan operation |
title_short | Catastrophic intracranial hemorrhage associated with eosinophilic granulomatous polyangiitis in a patient after Fontan operation |
title_sort | catastrophic intracranial hemorrhage associated with eosinophilic granulomatous polyangiitis in a patient after fontan operation |
topic | Case Reports |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7813104/ https://www.ncbi.nlm.nih.gov/pubmed/33489213 http://dx.doi.org/10.1002/ccr3.3579 |
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