An unusual and severe case of paclitaxel‐induced hand‐foot syndrome

Although paclitaxel is known to cause mild skin toxicity, it may induce severe HFS requiring drug withdrawal. Patients with high disease burden might receive prolonged paclitaxel chemotherapy. Hence, a grade 2 toxicity would better indicate withdrawal of paclitaxel instead of suspension and rechalle...

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Autores principales: Ben Abdallah, Ichrak, Ben Nasr, Sonia, Zribi, Aref, Ayarai, Jihene, Fendri, Sana, Mehdi, Balti, Abderrazek, Haddaoui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Clinical Images
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7813109/
https://www.ncbi.nlm.nih.gov/pubmed/33489227
http://dx.doi.org/10.1002/ccr3.3573
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author Ben Abdallah, Ichrak
Ben Nasr, Sonia
Zribi, Aref
Ayarai, Jihene
Fendri, Sana
Mehdi, Balti
Abderrazek, Haddaoui
author_facet Ben Abdallah, Ichrak
Ben Nasr, Sonia
Zribi, Aref
Ayarai, Jihene
Fendri, Sana
Mehdi, Balti
Abderrazek, Haddaoui
author_sort Ben Abdallah, Ichrak
collection PubMed
description Although paclitaxel is known to cause mild skin toxicity, it may induce severe HFS requiring drug withdrawal. Patients with high disease burden might receive prolonged paclitaxel chemotherapy. Hence, a grade 2 toxicity would better indicate withdrawal of paclitaxel instead of suspension and rechallenge, to prevent such severe HFS requiring long‐time recovery.
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spelling pubmed-78131092021-01-22 An unusual and severe case of paclitaxel‐induced hand‐foot syndrome Ben Abdallah, Ichrak Ben Nasr, Sonia Zribi, Aref Ayarai, Jihene Fendri, Sana Mehdi, Balti Abderrazek, Haddaoui Clin Case Rep Clinical Images Although paclitaxel is known to cause mild skin toxicity, it may induce severe HFS requiring drug withdrawal. Patients with high disease burden might receive prolonged paclitaxel chemotherapy. Hence, a grade 2 toxicity would better indicate withdrawal of paclitaxel instead of suspension and rechallenge, to prevent such severe HFS requiring long‐time recovery. John Wiley and Sons Inc. 2020-11-29 /pmc/articles/PMC7813109/ /pubmed/33489227 http://dx.doi.org/10.1002/ccr3.3573 Text en © 2020 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Clinical Images
Ben Abdallah, Ichrak
Ben Nasr, Sonia
Zribi, Aref
Ayarai, Jihene
Fendri, Sana
Mehdi, Balti
Abderrazek, Haddaoui
An unusual and severe case of paclitaxel‐induced hand‐foot syndrome
title An unusual and severe case of paclitaxel‐induced hand‐foot syndrome
title_full An unusual and severe case of paclitaxel‐induced hand‐foot syndrome
title_fullStr An unusual and severe case of paclitaxel‐induced hand‐foot syndrome
title_full_unstemmed An unusual and severe case of paclitaxel‐induced hand‐foot syndrome
title_short An unusual and severe case of paclitaxel‐induced hand‐foot syndrome
title_sort unusual and severe case of paclitaxel‐induced hand‐foot syndrome
topic Clinical Images
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7813109/
https://www.ncbi.nlm.nih.gov/pubmed/33489227
http://dx.doi.org/10.1002/ccr3.3573
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