CXCL13 shapes immunoactive tumor microenvironment and enhances the efficacy of PD-1 checkpoint blockade in high-grade serous ovarian cancer

BACKGROUND: Most patients with high-grade serous ovarian cancer (HGSC) lack an effective response to immune checkpoint blockade, highlighting the need for more knowledge about what is required for successful treatment. As follicular cytotoxic CXCR5(+)CD8(+) T cells are maintained by reinvigoration b...

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Detalles Bibliográficos
Autores principales: Yang, Moran, Lu, Jiaqi, Zhang, Guodong, Wang, Yiying, He, Mengdi, Xu, Qing, Xu, Congjian, Liu, Haiou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Immunotherapy Biomarkers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7813306/
https://www.ncbi.nlm.nih.gov/pubmed/33452206
http://dx.doi.org/10.1136/jitc-2020-001136

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7813306/
https://www.ncbi.nlm.nih.gov/pubmed/33452206
http://dx.doi.org/10.1136/jitc-2020-001136

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