Cargando…

Actinobacillus pleuropneumoniae exotoxin ApxI induces cell death via attenuation of FAK through LFA-1

ApxI exotoxin is an important virulence factor derived from Actinobacillus pleuropneumoniae that causes pleuropneumonia in swine. Here, we investigate the role of lymphocyte function-associated antigen 1 (LFA-1, CD11a/CD18), a member of the β(2) integrin family, and the involvement of the integrin s...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Siou-Cen, Cheng, Yu-Tsen, Wang, Ching-Yang, Wu, Jia-Ying, Chen, Zeng-Weng, Wang, Jyh-Perng, Lin, Jiunn-Horng, Hsuan, Shih-Ling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7813829/ https://www.ncbi.nlm.nih.gov/pubmed/33462305 http://dx.doi.org/10.1038/s41598-021-81290-9

Ejemplares similares

Elucidating the role of ApxI in hemolysis and cellular damage by using a novel apxIA mutant of Actinobacillus pleuropneumoniae serotype 10
por: Chang, Nai-Yun, et al.
Publicado: (2014)

Mechanisms underlying Actinobacillus pleuropneumoniae exotoxin ApxI induced expression of IL-1β, IL-8 and TNF-α in porcine alveolar macrophages
por: Chen, Zeng-Weng, et al.
Publicado: (2011)

Development of Actinobacillus pleuropneumoniae ApxI, ApxII, and ApxIII-specific ELISA methods for evaluation of vaccine efficiency
por: Jung, Myunghwan, et al.
Publicado: (2019)

In silico capsule locus typing for serovar prediction of Actinobacillus pleuropneumoniae
por: Li, Siou-Cen, et al.
Publicado: (2022)

An in vitro study of ApxI from Actinobacillus pleuropneumoniae serotype 10 and induction of NLRP3 inflammasome‐dependent cell death
por: Hernandez‐Cuellar, Eduardo, et al.
Publicado: (2021)

TurboID screening of ApxI toxin interactants identifies host proteins involved in Actinobacillus pleuropneumoniae-induced apoptosis of immortalized porcine alveolar macrophages
por: Hu, Yaofang, et al.
Publicado: (2023)

Cytoplasmic glycoengineering of Apx toxin fragments in the development of Actinobacillus pleuropneumoniae glycoconjugate vaccines
por: Passmore, Ian J., et al.
Publicado: (2019)

Porcine CD18 mediates Actinobacillus pleuropneumoniae ApxIII species-specific toxicity
por: Vanden Bergh, Philippe G.A.C., et al.
Publicado: (2009)

Immunological study of an attenuated Salmonella Typhimurium expressing ApxIA, ApxIIA, ApxIIIA and OmpA of Actinobacillus pleuropneumoniae in a mouse model
por: HUR, Jin, et al.
Publicado: (2015)

Isolation and characterization of atypical Actinobacillus pleuropneumoniae serovar 15 lacking the apxIICA genes in Japan
por: TESHIMA, Kaho, et al.
Publicado: (2019)

Enhancement of protective immune responses by oral vaccination with Saccharomyces cerevisiae expressing recombinant Actinobacillus pleuropneumoniae ApxIA or ApxIIA in mice
por: Shin, Sung Jae, et al.
Publicado: (2007)

Enhancement of Apx Toxin Production in Actinobacillus pleuropneumoniae Serotypes 1, 2, and 5 by Optimizing Culture Conditions
por: Dao, Hoai Thu, et al.
Publicado: (2020)

A CRISPR/Cas12a-assisted rapid detection platform by biosensing the apxIVA of Actinobacillus pleuropneumoniae
por: Luan, Tian, et al.
Publicado: (2022)

Sero- and apx-typing of German Actinobacillus pleuropneumoniae field isolates from 2010 to 2019 reveals a predominance of serovar 2 with regular apx-profile
por: Schuwerk, Lukas, et al.
Publicado: (2021)

Probing of Actinobacillus pleuropneumoniae ApxIIIA toxin-dependent cytotoxicity towards mammalian peripheral blood mononucleated cells
por: Vanden Bergh, Philippe GAC, et al.
Publicado: (2008)

Polymorphism analysis of the apxIA gene of Actinobacillus pleuropneumoniae serovar 5 isolated in swine herds from Brazil
por: dos Santos, Lucas Fernando, et al.
Publicado: (2018)

Construction and immunization with double mutant ΔapxIBD Δpnp forms of Actinobacillus pleuropneumoniae serotypes 1 and 5
por: Dao, Hoai Thu, et al.
Publicado: (2020)

Generation of transgenic corn-derived Actinobacillus pleuropneumoniae ApxIIA fused with the cholera toxin B subunit as a vaccine candidate
por: Shin, Min-Kyoung, et al.
Publicado: (2011)

Explorative Field Study on the Use of Oral Fluids for the Surveillance of Actinobacillus pleuropneumoniae Infections in Fattening Farms by an Apx-Real-Time PCR
por: Kleinmans, Michael, et al.
Publicado: (2022)

Detection of Actinobacillus Pleuropneumoniae ApxIV Toxin Antibody in Serum and Oral Fluid Specimens from Pigs Inoculated Under Experimental Conditions
por: González, Wendy, et al.
Publicado: (2017)

Attenuated Actinobacillus pleuropneumoniae double-deletion mutant S-8∆clpP/apxIIC confers protection against homologous or heterologous strain challenge
por: Xie, Fang, et al.
Publicado: (2017)

Global Gene Networks in 3D4/31 Porcine Alveolar Macrophages Treated with Antigenic Epitopes of Actinobacillus pleuropneumoniae ApxIA, IIA, and IVA
por: Kim, Suji, et al.
Publicado: (2019)

Actinobacillus pleuropneumoniae Interaction With Swine Endothelial Cells
por: Plasencia-Muñoz, Berenice, et al.
Publicado: (2020)

Novel DNA Markers for Identification of Actinobacillus pleuropneumoniae
por: Srijuntongsiri, Gun, et al.
Publicado: (2022)

Genetic Diversity of Actinobacillus pleuropneumoniae Serovars in Hungary
por: Kardos, Gábor, et al.
Publicado: (2022)

Effects of growth conditions on biofilm formation by Actinobacillus pleuropneumoniae
por: Labrie, Josée, et al.
Publicado: (2010)

Global Effects of Catecholamines on Actinobacillus pleuropneumoniae Gene Expression
por: Li, Lu, et al.
Publicado: (2012)

Actinobacillus pleuropneumoniae serovar 8 predominates in England and Wales
por: Li, Y., et al.
Publicado: (2016)

Identification and characterization of serovar-independent immunogens in Actinobacillus pleuropneumoniae
por: Antenucci, Fabio, et al.
Publicado: (2017)

Evaluation of multicomponent recombinant vaccines against Actinobacillus pleuropneumoniae in mice
por: Shao, Meili, et al.
Publicado: (2010)

Immunoproteomic analysis of bacterial proteins of Actinobacillus pleuropneumoniae serotype 1
por: Zhang, Wei, et al.
Publicado: (2011)

Transcriptional profiling of Actinobacillus pleuropneumoniae under iron-restricted conditions
por: Deslandes, Vincent, et al.
Publicado: (2007)

Genome-wide evidence for positive selection and recombination in Actinobacillus pleuropneumoniae
por: Xu, Zhuofei, et al.
Publicado: (2011)

Modulation of Gene Expression in Actinobacillus pleuropneumoniae Exposed to Bronchoalveolar Fluid
por: Lone, Abdul G., et al.
Publicado: (2009)

Isolation of Atypical Genotype Actinobacillus pleuropneumoniae Serotype 6 in Japan
por: ITO, Hiroya, et al.
Publicado: (2013)

Antibiofilm Activity of Actinobacillus pleuropneumoniae Serotype 5 Capsular Polysaccharide
por: Karwacki, Michael T., et al.
Publicado: (2013)

Method to grow Actinobacillus pleuropneumoniae biofilm on a biotic surface
por: Tremblay, Yannick DN, et al.
Publicado: (2013)

Catecholamines Promote Actinobacillus pleuropneumoniae Growth by Regulating Iron Metabolism
por: Li, Lu, et al.
Publicado: (2015)

In vivo testing of novel vaccine prototypes against Actinobacillus pleuropneumoniae
por: Antenucci, Fabio, et al.
Publicado: (2018)

Whole Genome Sequencing for Surveillance of Antimicrobial Resistance in Actinobacillus pleuropneumoniae
por: Bossé, Janine T., et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_umtqg0fjmphjrhgc1h34ccfi8p