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Adrenomedullin-CALCRL axis controls relapse-initiating drug tolerant acute myeloid leukemia cells

Drug tolerant/resistant leukemic stem cell (LSC) subpopulations may explain frequent relapses in acute myeloid leukemia (AML), suggesting that these relapse-initiating cells (RICs) persistent after chemotherapy represent bona fide targets to prevent drug resistance and relapse. We uncover that calci...

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Detalles Bibliográficos
Autores principales:	Larrue, Clément, Guiraud, Nathan, Mouchel, Pierre-Luc, Dubois, Marine, Farge, Thomas, Gotanègre, Mathilde, Bosc, Claudie, Saland, Estelle, Nicolau-Travers, Marie-Laure, Sabatier, Marie, Serhan, Nizar, Sahal, Ambrine, Boet, Emeline, Mouche, Sarah, Heydt, Quentin, Aroua, Nesrine, Stuani, Lucille, Kaoma, Tony, Angenendt, Linus, Mikesch, Jan-Henrik, Schliemann, Christoph, Vergez, François, Tamburini, Jérôme, Récher, Christian, Sarry, Jean-Emmanuel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7813857/ https://www.ncbi.nlm.nih.gov/pubmed/33462236 http://dx.doi.org/10.1038/s41467-020-20717-9

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