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Suppression of Hypertrophy During in vitro Chondrogenesis of Cocultures of Human Mesenchymal Stem Cells and Nasal Chondrocytes Correlates With Lack of in vivo Calcification and Vascular Invasion
OBJECTIVE: Human nasal septal chondrocytes (NC) are a promising minimally invasive derivable chondrogenic cell source for cartilage repair. However, the quality of NC-derived cartilage is variable between donors. Coculture of NC with mesenchymal stem cells (MSCs) mitigates the variability but with u...
Autores principales: | Anderson-Baron, Matthew, Liang, Yan, Kunze, Melanie, Mulet-Sierra, Aillette, Osswald, Martin, Ansari, Khalid, Seikaly, Hadi, Adesida, Adetola B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7813892/ https://www.ncbi.nlm.nih.gov/pubmed/33469528 http://dx.doi.org/10.3389/fbioe.2020.572356 |
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