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Single-Cell RNA Sequencing of Tocilizumab-Treated Peripheral Blood Mononuclear Cells as an in vitro Model of Inflammation

COVID-19 has posed a significant threat to global health. Early data has revealed that IL-6, a key regulatory cytokine, plays an important role in the cytokine storm of COVID-19. Multiple trials are therefore looking at the effects of Tocilizumab, an IL-6 receptor antibody that inhibits IL-6 activit...

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Detalles Bibliográficos
Autores principales:	Zarinsefat, Arya, Hartoularos, George, Rychkov, Dmitry, Rashmi, Priyanka, Chandran, Sindhu, Vincenti, Flavio, Yee, Chun J., Sarwal, Minnie M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7813999/ https://www.ncbi.nlm.nih.gov/pubmed/33469465 http://dx.doi.org/10.3389/fgene.2020.610682

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