A clinically applicable and scalable method to regenerate T-cells from iPSCs for off-the-shelf T-cell immunotherapy

Clinical successes demonstrated by chimeric antigen receptor T-cell immunotherapy have facilitated further development of T-cell immunotherapy against wide variety of diseases. One approach is the development of “off-the-shelf” T-cell sources. Technologies to generate T-cells from pluripotent stem c...

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Detalles Bibliográficos
Autores principales: Iriguchi, Shoichi, Yasui, Yutaka, Kawai, Yohei, Arima, Suguru, Kunitomo, Mihoko, Sato, Takayuki, Ueda, Tatsuki, Minagawa, Atsutaka, Mishima, Yuta, Yanagawa, Nariaki, Baba, Yuji, Miyake, Yasuyuki, Nakayama, Kazuhide, Takiguchi, Maiko, Shinohara, Tokuyuki, Nakatsura, Tetsuya, Yasukawa, Masaki, Kassai, Yoshiaki, Hayashi, Akira, Kaneko, Shin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7814014/
https://www.ncbi.nlm.nih.gov/pubmed/33462228
http://dx.doi.org/10.1038/s41467-020-20658-3

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