Cargando…

Genotoxic risk assessment and mechanism of DNA damage induced by phthalates and their metabolites in human peripheral blood mononuclear cells

The human genome is persistently exposed to damage caused by xenobiotics, therefore the assessment of genotoxicity of substances having a direct contact with humans is of importance. Phthalates are commonly used in industrial applications. Widespread exposure to phthalates has been evidenced by thei...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sicińska, Paulina, Mokra, Katarzyna, Wozniak, Katarzyna, Michałowicz, Jaromir, Bukowska, Bożena
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7814068/ https://www.ncbi.nlm.nih.gov/pubmed/33462290 http://dx.doi.org/10.1038/s41598-020-79932-5

Ejemplares similares

Genotoxic Mechanism of Action of TBBPA, TBBPS and Selected Bromophenols in Human Peripheral Blood Mononuclear Cells
por: Barańska, Anna, et al.
Publicado: (2022)

Benzo[a]pyrene—Environmental Occurrence, Human Exposure, and Mechanisms of Toxicity
por: Bukowska, Bożena, et al.
Publicado: (2022)

Apoptosis-Inducing Potential of Selected Bromophenolic Flame Retardants 2,4,6-Tribromophenol and Pentabromophenol in Human Peripheral Blood Mononuclear Cells
por: Barańska, Anna, et al.
Publicado: (2022)

Determination of Apoptotic Mechanism of Action of Tetrabromobisphenol A and Tetrabromobisphenol S in Human Peripheral Blood Mononuclear Cells: A Comparative Study
por: Barańska, Anna, et al.
Publicado: (2022)

The Impact of Glyphosate, Its Metabolites and Impurities on Viability, ATP Level and Morphological changes in Human Peripheral Blood Mononuclear Cells
por: Kwiatkowska, Marta, et al.
Publicado: (2016)

Human Erythrocytes Exposed to Phthalates and Their Metabolites Alter Antioxidant Enzyme Activity and Hemoglobin Oxidation
por: Sicińska, Paulina, et al.
Publicado: (2020)

Glyphosate and AMPA Induce Alterations in Expression of Genes Involved in Chromatin Architecture in Human Peripheral Blood Mononuclear Cells (In Vitro)
por: Woźniak, Ewelina, et al.
Publicado: (2021)

Oxidative Properties of Polystyrene Nanoparticles with Different Diameters in Human Peripheral Blood Mononuclear Cells (In Vitro Study)
por: Kik, Kinga, et al.
Publicado: (2021)

Influence of Benzo(a)pyrene on Different Epigenetic Processes
por: Bukowska, Bożena, et al.
Publicado: (2021)

Changes in Human Erythrocyte Membrane Exposed to Aqueous and Ethanolic Extracts from Uncaria tomentosa
por: Duchnowicz, Piotr, et al.
Publicado: (2021)

Evaluation of In Vitro Genotoxicity of Polystyrene Nanoparticles in Human Peripheral Blood Mononuclear Cells
por: Babonaitė, Milda, et al.
Publicado: (2023)

The Protective Effect of Dabigatran and Rivaroxaban on DNA Oxidative Changes in a Model of Vascular Endothelial Damage with Oxidized Cholesterol
por: Woźniak, Ewelina, et al.
Publicado: (2020)

The benzene metabolite para-benzoquinone is genotoxic in human, phorbol-12-acetate-13-myristate induced, peripheral blood mononuclear cells at low concentrations
por: Westphal, Götz Alexander, et al.
Publicado: (2009)

Assessment of Cytotoxic, Genotoxic, and Oxidative Stress of Dibutyl Phthalate on Cultured Bovine Peripheral Lymphocytes
por: Ali, Muhammad Muddassir, et al.
Publicado: (2022)

DNA damage in peripheral blood mononuclear cells and neutrophils of dairy cows during the transition period
por: Tharwat, M., et al.
Publicado: (2012)

Monitoring DNA Damage and Repair in Peripheral Blood Mononuclear Cells of Lung Cancer Radiotherapy Patients
por: Lobachevsky, Pavel N., et al.
Publicado: (2020)

Decreased activity of butyrylcholinesterase in blood plasma of patients with chronic obstructive pulmonary disease
por: Sicinska, Paulina, et al.
Publicado: (2016)

The DNA Methylome of Human Peripheral Blood Mononuclear Cells
por: Li, Yingrui, et al.
Publicado: (2010)

Age and metabolic risk factors associated with oxidatively damaged DNA in human peripheral blood mononuclear cells
por: Løhr, Mille, et al.
Publicado: (2014)

A higher throughput assay for quantification of melphalan-induced DNA damage in peripheral blood mononuclear cells
por: van Kan, Maia, et al.
Publicado: (2019)

Phthalates and phthalate metabolites in urine from Tianjin and implications for platelet mitochondrial DNA methylation
por: Li, Weixia, et al.
Publicado: (2023)

Oxidative Stress-Induced DNA Damage and Repair in Human Peripheral Blood Mononuclear Cells: Protective Role of Hemoglobin
por: Gafter-Gvili, Anat, et al.
Publicado: (2013)

DNA damage and repair in peripheral blood mononuclear cells after internal ex vivo irradiation of patient blood with (131)I
por: Schumann, S., et al.
Publicado: (2021)

Genetic toxicology of phthalate esters: mutagenic and other genotoxic effects.
por: Douglas, G R, et al.
Publicado: (1986)

Increased nuclear DNA damage precedes mitochondrial dysfunction in peripheral blood mononuclear cells from Huntington’s disease patients
por: Askeland, Georgina, et al.
Publicado: (2018)

Protective Effect of Melatonin Against Mitomycin C-Induced Genotoxic Damage in Peripheral Blood of Rats
por: Ortega-Gutiérrez, S., et al.
Publicado: (2009)

Protein versus DNA as a marker for peripheral blood mononuclear cell counting
por: Jansen, Robert S., et al.
Publicado: (2009)

Peripheral Blood Mononuclear Cells HIV DNA Levels Impact Intermittently on Neurocognition
por: Cysique, Lucette A., et al.
Publicado: (2015)

Colonic Bacteria-Transformed Catechin Metabolite Response to Cytokine Production by Human Peripheral Blood Mononuclear Cells
por: Krishnamoorthy, Rajapandiyan, et al.
Publicado: (2019)

Endocrine Disruptor Potential of Short- and Long-Chain Perfluoroalkyl Substances (PFASs)—A Synthesis of Current Knowledge with Proposal of Molecular Mechanism
por: Mokra, Katarzyna
Publicado: (2021)

Whole blood as an alternative to peripheral blood mononuclear cell for detection of total HIV-1 DNA
por: Lin, Ling, et al.
Publicado: (2020)

The Transcriptome of Equine Peripheral Blood Mononuclear Cells
por: Pacholewska, Alicja, et al.
Publicado: (2015)

Genotoxicity, DNA damage and sperm defects induced by vinblastine
por: Fahmy, Maha A., et al.
Publicado: (2022)

No oxidative stress or DNA damage in peripheral blood mononuclear cells after exposure to particles from urban street air in overweight elderly
por: Hemmingsen, Jette Gjerke, et al.
Publicado: (2015)

Repair of α-particle-induced DNA damage in peripheral blood mononuclear cells after internal ex vivo irradiation with (223)Ra
por: Göring, Lukas, et al.
Publicado: (2022)

Genotoxicity and Immunotoxicity of Titanium Dioxide-Embedded Mesoporous Silica Nanoparticles (TiO(2)@MSN) in Primary Peripheral Human Blood Mononuclear Cells (PBMC)
por: Di Giampaolo, Luca, et al.
Publicado: (2021)

The correlation between pretreatment cytokine expression patterns in peripheral blood mononuclear cells with chronic hepatitis c outcome
por: Jabłońska, Joanna, et al.
Publicado: (2015)

The signature of HBV-related liver disease in peripheral blood mononuclear cell DNA methylation
por: Li, Kang, et al.
Publicado: (2020)

Impact of Human Umbilical Cord Blood Mononuclear Cells on Gentamicin-Induced Renal Injury and Genotoxicity in Rats
por: Abu Almaaty, Ali H., et al.
Publicado: (2021)

Prenatal phthalate exposure and cord blood DNA methylation
por: Lee, Jooah, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_6n10p9gk0i4kk26ievi1mamsdr