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Necrotising otitis externa: A single centre experience

INTRODUCTION: Necrotising otitis externa (NOE) is a rare infection of the ear canal with frequent bone erosion. This study’s objective is to describe the different features of NOE as well as its management in an ear-nose-throat department. We also tried to identify the particularities of the fungal...

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Autores principales: Hasnaoui, Mehdi, Ben Mabrouk, Asma, Chelli, Jihene, Larbi Ammari, Fatma, Lahmar, Rihab, Toumi, Adnene, Mighri, Khalifa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chinese PLA General Hospital 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7814081/
https://www.ncbi.nlm.nih.gov/pubmed/33505446
http://dx.doi.org/10.1016/j.joto.2020.07.005
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author Hasnaoui, Mehdi
Ben Mabrouk, Asma
Chelli, Jihene
Larbi Ammari, Fatma
Lahmar, Rihab
Toumi, Adnene
Mighri, Khalifa
author_facet Hasnaoui, Mehdi
Ben Mabrouk, Asma
Chelli, Jihene
Larbi Ammari, Fatma
Lahmar, Rihab
Toumi, Adnene
Mighri, Khalifa
author_sort Hasnaoui, Mehdi
collection PubMed
description INTRODUCTION: Necrotising otitis externa (NOE) is a rare infection of the ear canal with frequent bone erosion. This study’s objective is to describe the different features of NOE as well as its management in an ear-nose-throat department. We also tried to identify the particularities of the fungal infection. PATIENTS AND METHODS: It is an observational cohort that included all the patients hospitalised for the management of NOE. The study was carried out in the ear-nose-throat Department of Mahdia University Hospital in Tunisia between January 2006 and december 2019. RESULTS: A total of 40 patients were included. The mean age was 65 ± 12.9 years and the sex ratio was 0.9. Ninety percent of the patients included were diabetics. The most common signs found were oedema of the external canal (97.5%) and auricular discharge (92.5%). The main pathogen isolated was Pseudomonas aeruginosa (61.7%). Fungi were isolated in 9 cases (26.47%). Computed tomography was performed for 32 patients (80%). Bone erosion was seen in 26 cases (81.3%). The main complications were cerebral venous thrombosis, retropharyngeal abscess and cerebral empyema. Thirty one patients received only antibiotics, 2 received only antifungal treatment, and 7 received both antibiotics and antifungal treatment. All patients had a favorable outcome. Univariate analysis showed a higher median erythrocyte sedimentation rate was associated with fungal infections. No other differences were noted. CONCLUSION: Our management protocol seems to be efficient since all patients had initial favorable outcome. A higher median erythrocyte sedimentation rate was associated with fungal infections.
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spelling pubmed-78140812021-01-26 Necrotising otitis externa: A single centre experience Hasnaoui, Mehdi Ben Mabrouk, Asma Chelli, Jihene Larbi Ammari, Fatma Lahmar, Rihab Toumi, Adnene Mighri, Khalifa J Otol Research Article INTRODUCTION: Necrotising otitis externa (NOE) is a rare infection of the ear canal with frequent bone erosion. This study’s objective is to describe the different features of NOE as well as its management in an ear-nose-throat department. We also tried to identify the particularities of the fungal infection. PATIENTS AND METHODS: It is an observational cohort that included all the patients hospitalised for the management of NOE. The study was carried out in the ear-nose-throat Department of Mahdia University Hospital in Tunisia between January 2006 and december 2019. RESULTS: A total of 40 patients were included. The mean age was 65 ± 12.9 years and the sex ratio was 0.9. Ninety percent of the patients included were diabetics. The most common signs found were oedema of the external canal (97.5%) and auricular discharge (92.5%). The main pathogen isolated was Pseudomonas aeruginosa (61.7%). Fungi were isolated in 9 cases (26.47%). Computed tomography was performed for 32 patients (80%). Bone erosion was seen in 26 cases (81.3%). The main complications were cerebral venous thrombosis, retropharyngeal abscess and cerebral empyema. Thirty one patients received only antibiotics, 2 received only antifungal treatment, and 7 received both antibiotics and antifungal treatment. All patients had a favorable outcome. Univariate analysis showed a higher median erythrocyte sedimentation rate was associated with fungal infections. No other differences were noted. CONCLUSION: Our management protocol seems to be efficient since all patients had initial favorable outcome. A higher median erythrocyte sedimentation rate was associated with fungal infections. Chinese PLA General Hospital 2021-01 2020-07-29 /pmc/articles/PMC7814081/ /pubmed/33505446 http://dx.doi.org/10.1016/j.joto.2020.07.005 Text en © 2020 PLA General Hospital Department of Otolaryngology Head and Neck Surgery. Production and hosting by Elsevier (Singapore) Pte Ltd. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Research Article
Hasnaoui, Mehdi
Ben Mabrouk, Asma
Chelli, Jihene
Larbi Ammari, Fatma
Lahmar, Rihab
Toumi, Adnene
Mighri, Khalifa
Necrotising otitis externa: A single centre experience
title Necrotising otitis externa: A single centre experience
title_full Necrotising otitis externa: A single centre experience
title_fullStr Necrotising otitis externa: A single centre experience
title_full_unstemmed Necrotising otitis externa: A single centre experience
title_short Necrotising otitis externa: A single centre experience
title_sort necrotising otitis externa: a single centre experience
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7814081/
https://www.ncbi.nlm.nih.gov/pubmed/33505446
http://dx.doi.org/10.1016/j.joto.2020.07.005
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