Adjunctive Statin Therapy Reduces Mortality After Acute Hemorrhagic Stroke

BACKGROUND: Statin treatment improves clinical outcomes in patients with ischemic strokes, although there is no evidence regarding the safety of statin therapy in patients with intracerebral hemorrhage (ICH). This study aimed at evaluating the effects of continuing statin treatment after ICH. METHOD...

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Detalles Bibliográficos
Autores principales: Lin, Cheng-Kai, Chen, Po-Yuan, Wu, Yu-ying, Wu, Cheng-Chun, Chen, Han-Jung, Liang, Cheng-Loong, Lee, Yi-Che, Lin, Chi-Wei, Hung, Chao-Ming, Wang, Hao-Kuang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7814233/
https://www.ncbi.nlm.nih.gov/pubmed/33488130
http://dx.doi.org/10.2147/RMHP.S290964
Descripción
Sumario:BACKGROUND: Statin treatment improves clinical outcomes in patients with ischemic strokes, although there is no evidence regarding the safety of statin therapy in patients with intracerebral hemorrhage (ICH). This study aimed at evaluating the effects of continuing statin treatment after ICH. METHODS: Data were obtained from the National Health Insurance Research Database in Taiwan. We retrospectively compared the data of patients with and without statin exposure after ICH. The outcomes of interest were recurrence of hemorrhagic stroke and mortality during a follow-up period of 10 years. RESULTS: During the 10-year follow-up period, the mortality rate was 32.73% in the statin group and 42.77% in the non-statin group. Statin therapy in patients with acute ICH with dyslipidemia can decrease mortality. CONCLUSION: Statin therapy reduced the risk of 10-year mortality in patients who experienced acute hemorrhagic stroke.

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