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11-Oxygenated Estrogens Are a Novel Class of Human Estrogens but Do not Contribute to the Circulating Estrogen Pool

Androgens are the obligatory precursors of estrogens. In humans, classic androgen biosynthesis yields testosterone, thought to represent the predominant circulating active androgen both in men and women. However, recent work has shown that 11-ketotestosterone, derived from the newly described 11-oxy...

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Detalles Bibliográficos
Autores principales: Barnard, Lise, Schiffer, Lina, Louw du-Toit, Renate, Tamblyn, Jennifer A, Chen, Shiuan, Africander, Donita, Arlt, Wiebke, Foster, Paul A, Storbeck, Karl-Heinz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7814299/
https://www.ncbi.nlm.nih.gov/pubmed/33340399
http://dx.doi.org/10.1210/endocr/bqaa231