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Candida auris Colonization After Discharge to a Community Setting: New York City, 2017–2019

BACKGROUND: Patients colonized with multidrug-resistant Candida auris and discharged to a community setting can subsequently seek care in a different healthcare facility and might be a source of nosocomial transmission of C auris. METHODS: We designed a case management pilot program for a cohort of...

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Detalles Bibliográficos
Autores principales: Bergeron, Genevieve, Bloch, Danielle, Murray, Kenya, Kratz, Molly, Parton, Hilary, Ackelsberg, Joel, Antwi, Mike, Del Rosso, Paula, Dorsinville, Marie, Kubinson, Hannah, Lash, Maura, Rand, Sophie, Adams, Eleanor, Zhu, Yanchun, Erazo, Richard, Chaturvedi, Sudha, Weiss, Don
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7814391/
https://www.ncbi.nlm.nih.gov/pubmed/33511238
http://dx.doi.org/10.1093/ofid/ofaa620
Descripción
Sumario:BACKGROUND: Patients colonized with multidrug-resistant Candida auris and discharged to a community setting can subsequently seek care in a different healthcare facility and might be a source of nosocomial transmission of C auris. METHODS: We designed a case management pilot program for a cohort of New York City residents who had a history of positive C auris culture identified during clinical or screening activities in healthcare settings and discharged to a community setting during 2017–2019. Approximately every 3 months, case managers coordinated C auris colonization assessments, which included swabs of groin, axilla, and body sites yielding C auris previously. Patients eligible to become serially negative were those with ≥2 C auris colonization assessments after initial C auris identification. Clinical characteristics of serially negative and positive patients were compared. RESULTS: The cohort included 75 patients. Overall, 45 patients were eligible to become serially negative and had 552 person-months of follow-up. Of these 45 patients, 28 patients were serially negative (62%; rate 5.1/100 person-months), 8 were serially positive, and 9 could not be classified as either. There were no clinical characteristics that were significantly different between serially negative and positive patients. The median time from initial C auris identification to being serially negative at assessments was 8.6 months (interquartile range, 5.7–10.8 months). CONCLUSIONS: A majority of patients, assessed at least twice after C auris identification, no longer had C auris detectable on serial colonization assessments.