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Hypoxia-induced Tie1 drives stemness and cisplatin resistance in non-small cell lung carcinoma cells

BACKGROUND: Drug resistance and metastasis involving hypoxic tumor environments and persistent stem cell populations are detrimental to the survival of patients with non-small cell lung carcinoma (NSCLC). Tie1 is upregulated in hypoxia and is believed to counteract the effectiveness of platinum agen...

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Detalles Bibliográficos
Autores principales:	Li, Chaojie, Yang, Nannan, Chen, Zhijin, Xia, Ning, Shan, Qungang, Wang, Ziyin, Lu, Jian, Shang, Mingyi, Wang, Zhongmin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7814430/ https://www.ncbi.nlm.nih.gov/pubmed/33461544 http://dx.doi.org/10.1186/s12935-020-01729-3

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