Major motor and gait deficits with sexual dimorphism in a Shank3 mutant mouse model

BACKGROUND: Contrasting findings were reported in several animal models with a Shank3 mutation used to induce various autism spectrum disorder (ASD) symptoms. Here, we aimed at investigating behavioral, cellular, and molecular consequences of a C-terminal (frameshift in exon 21) deletion in Shank3 p...

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Detalles Bibliográficos
Autores principales: Matas, Emmanuel, Maisterrena, Alexandre, Thabault, Mathieu, Balado, Eric, Francheteau, Maureen, Balbous, Anais, Galvan, Laurie, Jaber, Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7814442/
https://www.ncbi.nlm.nih.gov/pubmed/33468258
http://dx.doi.org/10.1186/s13229-020-00412-8

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