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A rare large duplication of MLH1 identified in Lynch syndrome

BACKGROUND: The most frequently identified strong cancer predisposition mutations for colorectal cancer (CRC) are those in the mismatch repair (MMR) genes in Lynch syndrome. Laboratory diagnostics include testing tumors for immunohistochemical staining (IHC) of the Lynch syndrome-associated DNA MMR...

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Detalles Bibliográficos
Autores principales:	Kumar, Abhishek, Paramasivam, Nagarajan, Bandapalli, Obul Reddy, Schlesner, Matthias, Chen, Tianhui, Sijmons, Rolf, Dymerska, Dagmara, Golebiewska, Katarzyna, Kuswik, Magdalena, Lubinski, Jan, Hemminki, Kari, Försti, Asta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7814444/ https://www.ncbi.nlm.nih.gov/pubmed/33468175 http://dx.doi.org/10.1186/s13053-021-00167-0

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