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Klotho retards renal fibrosis through targeting mitochondrial dysfunction and cellular senescence in renal tubular cells

Chronic kidney disease (CKD) has a high prevalence worldwide and is an intricate issue to whole medical society. Renal fibrosis is the common pathological feature for various kinds of CKD. As an anti‐aging protein, Klotho is predominantly expressed in renal tubular epithelial cells. Reports show Klo...

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Detalles Bibliográficos
Autores principales: Miao, Jinhua, Huang, Jiewu, Luo, Congwei, Ye, Huiyun, Ling, Xian, Wu, Qinyu, Shen, Weiwei, Zhou, Lili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7814487/
https://www.ncbi.nlm.nih.gov/pubmed/33463897
http://dx.doi.org/10.14814/phy2.14696