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Dysregulated follicular regulatory T cells and antibody responses exacerbate experimental autoimmune encephalomyelitis
BACKGROUND: Follicular regulatory T (T(FR)) cells are essential for the regulation of germinal center (GC) response and humoral self-tolerance. Dysregulated follicular helper T (T(FH)) cell-GC-antibody (Ab) response secondary to dysfunctional T(FR) cells is the root of an array of autoimmune disorde...
Autores principales: | Luo, Lin, Hu, Xianzhen, Dixon, Michael L., Pope, Brandon J., Leavenworth, Jonathan D., Raman, Chander, Meador, William R., Leavenworth, Jianmei W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7814531/ https://www.ncbi.nlm.nih.gov/pubmed/33468194 http://dx.doi.org/10.1186/s12974-021-02076-4 |
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