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Bioinformatics analysis of miRNA and mRNA expression profiles to reveal the key miRNAs and genes in osteoarthritis

BACKGROUND: Osteoarthritis (OA) is a chronic degenerative joint disease and the most frequent type of arthritis. This study aimed to identify the key miRNAs and genes associated with OA progression. METHODS: The GSE105027 (microRNA [miRNA/miR] expression profile; 12 OA samples and 12 normal samples)...

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Detalles Bibliográficos
Autores principales: Huang, Pei-yan, Wu, Jun-guo, Gu, Jun, Zhang, Tie-qi, Li, Ling-feng, Wang, Si-qun, Wang, Minghai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7814623/
https://www.ncbi.nlm.nih.gov/pubmed/33468167
http://dx.doi.org/10.1186/s13018-021-02201-2