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Synthetic Biology Driven Biosynthesis of Unnatural Tropolone Sesquiterpenoids

Tropolone sesquiterpenoids (TS) are an intriguing family of biologically active fungal meroterpenoids that arise through a unique intermolecular hetero Diels–Alder (hDA) reaction between humulene and tropolones. Here, we report on the combinatorial biosynthesis of a series of unprecedented analogs o...

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Detalles Bibliográficos
Autores principales: Schotte, Carsten, Li, Lei, Wibberg, Daniel, Kalinowski, Jörn, Cox, Russell J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7814671/
https://www.ncbi.nlm.nih.gov/pubmed/32929811
http://dx.doi.org/10.1002/anie.202009914