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rs1990622 variant associates with Alzheimer’s disease and regulates TMEM106B expression in human brain tissues

BACKGROUND: It has been well established that the TMEM106B gene rs1990622 variant was a frontotemporal dementia (FTD) risk factor. Until recently, growing evidence highlights the role of TMEM106B in Alzheimer’s disease (AD). However, it remains largely unclear about the role of rs1990622 variant in...

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Detalles Bibliográficos
Autores principales: Hu, Yang, Sun, Jing-yi, Zhang, Yan, Zhang, Haihua, Gao, Shan, Wang, Tao, Han, Zhifa, Wang, Longcai, Sun, Bao-liang, Liu, Guiyou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7814705/
https://www.ncbi.nlm.nih.gov/pubmed/33461566
http://dx.doi.org/10.1186/s12916-020-01883-5