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rs1990622 variant associates with Alzheimer’s disease and regulates TMEM106B expression in human brain tissues
BACKGROUND: It has been well established that the TMEM106B gene rs1990622 variant was a frontotemporal dementia (FTD) risk factor. Until recently, growing evidence highlights the role of TMEM106B in Alzheimer’s disease (AD). However, it remains largely unclear about the role of rs1990622 variant in...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7814705/ https://www.ncbi.nlm.nih.gov/pubmed/33461566 http://dx.doi.org/10.1186/s12916-020-01883-5 |