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Ferulic acid alleviates lipotoxicity-induced hepatocellular death through the SIRT1-regulated autophagy pathway and independently of AMPK and Akt in AML-12 hepatocytes

BACKGROUND: Lipotoxicity-induced cell death plays a detrimental role in the pathogenesis of metabolic diseases. Ferulic acid, widespread in plant-based food, is a radical scavenger with multiple bioactivities. However, the benefits of ferulic acid against hepatic lipotoxicity are largely unclear. He...

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Detalles Bibliográficos
Autores principales:	Xu, Tiantian, Song, Qing, Zhou, Li, Yang, Wenwen, Wu, Xiangyao, Qian, Qianyu, Chai, Hui, Han, Qiang, Pan, Hongzhi, Dou, Xiaobing, Li, Songtao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7814733/ https://www.ncbi.nlm.nih.gov/pubmed/33468182 http://dx.doi.org/10.1186/s12986-021-00540-9

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