Male sex and age biases viral burden, viral shedding, and type 1 and 2 interferon responses during SARS-CoV-2 infection in ferrets

SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) hospitalizations and deaths disportionally affect males and the elderly. Here we investigated the impact of male sex and age by infecting adult male, aged male, and adult female ferrets with SARS-CoV-2. Aged male ferrets had a decrease in...

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Detalles Bibliográficos
Autores principales: Francis, Magen E., Richardson, Brian, McNeil, Mara, Rioux, Melissa, Foley, Mary K., Ge, Anni, Pechous, Roger D., Kindrachuk, Jason, Cameron, Cheryl M., Richardson, Christopher, Lew, Jocelyne, Cameron, Mark J., Gerdts, Volker, Falzarano, Darryl, Kelvin, Alyson A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7814824/
https://www.ncbi.nlm.nih.gov/pubmed/33469587
http://dx.doi.org/10.1101/2021.01.12.426381

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7814824/
https://www.ncbi.nlm.nih.gov/pubmed/33469587
http://dx.doi.org/10.1101/2021.01.12.426381

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